abstract：PURPOSE OF REVIEW:Heart failure is a worldwide epidemic. Aggressive treatment of patients at risk for heart failure is important. There are no trials targeting primary prevention of heart failure. However, there is trial data demonstrating that treatment of patients with atherosclerotic vascular disease, hypertension, ...

journal_title：Current opinion in cardiology

authors： Dupree CS

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Many patients requiring cardiac arrhythmia device surgery are on chronic oral anticoagulation therapy. The periprocedural management of their anticoagulation presents a dilemma to physicians, particularly in the subset of patients with moderate-to-high risk of arterial thromboembolic events. Physician...

journal_title：Current opinion in cardiology

authors： Birnie D,Healey JS,Krahn A,Essebag V,Sivakumaran S,Tang A,Simpson C

更新日期：2009-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To illustrate the limitations of predictive risk models in cardiac surgery, highlight the difficulty in interpreting risk-adjusted outcome analysis and discuss the challenges of making clinical decisions based on risk predictions, particularly in high-risk patients. RECENT FINDINGS:Predictive risk mo...

journal_title：Current opinion in cardiology

authors： Dupuis JY

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the evidence supporting genetic predisposition to coronary artery disease (CAD). Secondly, to elucidate the barriers precluding the identification of genes responsible for CAD. Thirdly, to indicate the new technology now available to overcome these barriers and summarize current progress. R...

journal_title：Current opinion in cardiology

authors： Roberts R

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize changing paradigms and perceptions in the prevention and treatment of cardiovascular disease. RECENT FINDINGS:Recent studies have shown that arterial inflammation probably plays a key role in the development and progression of atherosclerosis, that acute myocardial infarctions often evol...

journal_title：Current opinion in cardiology

authors： Franklin BA,Trivax JE,Vanhecke TE

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Troponins are a cornerstone for the diagnosis of myocardial infarction, assessment of risk and prognosis, and determination of antithrombotic and a revascularization strategy in patients with acute coronary syndromes. Newer assays with higher precision for detection of troponin levels are about to ent...

journal_title：Current opinion in cardiology

authors： White HD

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The possible role of several neurohormonal factors in pathogenesis of hypertension has been studied extensively both in humans and in experimental animal models. However, controversial data from some previous studies are indecisive and call for reassessment and development of new targets. This mini-re...

journal_title：Current opinion in cardiology

authors： Wang DH

更新日期：2008-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To review trends in practice for mitral valve surgery in the US over the past decade. RECENT FINDINGS:Advances in the understanding of mitral valve pathophysiology and the technology involved with mitral valve surgery have led to significant changes of the current practice for mitral valve surgery, w...

journal_title：Current opinion in cardiology

authors： Ad N,Barnett SD,Speir AM,Massimiano PS

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Ablation for atrial fibrillation has become a widely accepted and practiced treatment for this arrhythmia. While this treatment has traditionally been reserved for second-line therapy in patients who have failed drug therapy, ablation is now being contemplated for first-line treatment. This review out...

journal_title：Current opinion in cardiology

authors： Verma A

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:With wider indications for implantable cardioverter defibrillator therapy, more patients at lower risk for ventricular tachyarrhythmia receive this treatment. To maintain the ratio of benefit versus side-effects at an acceptable level, the risk of inappropriate implantable cardioverter defibrillator t...

journal_title：Current opinion in cardiology

authors： Israel CW

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:In the era of percutaneous coronary intervention, surgeons are confronted with performing coronary artery bypass graft surgery on patients with previous balloon dilatation or stenting. This review evaluates the impact of previous percutaneous coronary intervention on patient survival and choice of opt...

journal_title：Current opinion in cardiology

authors： Al-Attar N,Nataf P

更新日期：2007-11-01 00:00:00

abstract：PURPOSE OF REVIEW:While the prognostic power of adenosine single photon emission computed tomography myocardial perfusion imaging has been validated in multiple patient populations including those with known or suspected coronary artery disease, the utility of this modality in assessing risk after an acute myocardial i...

journal_title：Current opinion in cardiology

authors： Dorfman TA,Iskandrian AE

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Valvular heart disease is often associated with significant morbidity and mortality. Surgical treatment of stenotic or regurgitant valvular lesions can alter the natural history of the disease process, yielding excellent short and long-term results, meaning that this has been accepted as the gold stan...

journal_title：Current opinion in cardiology

authors： Sinha AK,Kini AS,Sharma SK

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review focuses on new trends in genome-wide assessment of the inherited component of blood pressure variation. RECENT FINDINGS:Systematic linkage and association analyses of a region on chromosome 1q, complemented by gene prioritization with comparative genomic evidence, revealed variants...

journal_title：Current opinion in cardiology

authors： Hamet P,Seda O

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To compare the potential of high-density lipoprotein (HDL) cholesterol and apolipoprotein (apo) A-I, the major protein in HDL particles, in predicting cardiovascular risk. Pros and cons for using these risk markers are discussed. RECENT FINDINGS:Both HDL cholesterol and apoA-I are in most clinical co...

journal_title：Current opinion in cardiology

authors： Walldius G,Jungner I

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progressive improvement in surgical results, hypoplastic left heart syndrome remains one of the congenital heart abnormalities with the greatest morbidity and mortality. Hybrid approaches to management, combining surgical and interventional catheterization procedures, have been introduced to m...

journal_title：Current opinion in cardiology

authors： Gutgesell HP,Lim DS

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The prevention and treatment of rejection have been the major focus of clinical and research studies since the inception of heart transplantation. Recent improvement in survival after transplant has been in large part due to continued advancement in antirejection therapies. RECENT FINDINGS:The combin...

journal_title：Current opinion in cardiology

authors： Chan M,Pearson GJ

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation after cardiac surgery is associated with adverse outcomes and increased costs. Accordingly, therapy should be provided to prevent postoperative atrial fibrillation. The evaluation of therapies to do so is an area of active investigation with significant recent advances. The purpose...

journal_title：Current opinion in cardiology

authors： Mitchell LB

更新日期：2007-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to review the current status of optimal revascularization strategies in patients presenting with multivessel coronary artery disease. RECENT FINDINGS:Coronary artery bypass surgery is the gold standard for patients with multivessel disease. Recent developments in the interv...

journal_title：Current opinion in cardiology

authors： Daemen J,Serruys PW

更新日期：2006-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac magnetic resonance imaging has an expanding role as a preferred modality for the detection and characterization of myocardial viability. RECENT FINDINGS:Improving the accuracy of cardiac magnetic resonance for detecting viable myocardium has been one focus of investigators. In segments with i...

journal_title：Current opinion in cardiology

authors： Isbell DC,Kramer CM

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Hypertension and dyslipidemia frequently coexist, and endothelial dysfunction is associated with the pathophysiology of both atherosclerosis and hypertension. Evidence is convincing for an overlapping role of oxidative stress, renin-angiotensin system activation, and dyslipidemia in the genesis of end...

journal_title：Current opinion in cardiology

authors： Sarkar K,Sinha AK,Mehta JL

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:beta-Blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists, and digoxin are the most common drug classes used to treat chronic heart failure. We examine current clinical trial evidence concerning heart-failure management in the elderly. ...

journal_title：Current opinion in cardiology

authors： Dulin BR,Krum H

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Atrial fibrillation is the most common sustained cardiac arrhythmia and may cause significant morbidity. Current management strategies offer only modest success and may be associated with intolerable drug side effects or risk of procedural complications. As with other cardiac arrhythmias, the identifi...

journal_title：Current opinion in cardiology

authors： Gollob MH

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to update the cardiovascular clinician on the current status of surgical therapies aimed at achieving reverse ventricular remodeling. RECENT FINDINGS:Relevant research focusing on mechanical options for reverse ventricular remodeling will be referenced and summarized. SUMMA...

journal_title：Current opinion in cardiology

authors： McGee EC,Gillinov AM,McCarthy PM

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Device therapy for atrial fibrillation remains contentious despite the recognized benefit of atrial pacing in sinus node dysfunction. There are various new specialized pacing algorithms that aim to provide rhythm or rate control in atrial fibrillation. We review the various options for device therapy ...

journal_title：Current opinion in cardiology

authors： Redfearn DP,Yee R

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Cardiac transplantation is a recognized therapy for end-stage heart failure. Graft coronary artery disease is a chief determinant of long-term survival following cardiac transplantation. There are multiple purported etiologies for graft coronary artery disease including both immunologic and nonimmunol...

journal_title：Current opinion in cardiology

authors： Kass M,Haddad H

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Radiofrequency ablation techniques to cure cardiac arrhythmias have focused on destroying myocardial tissue involved in abnormal excitation or conduction. This review will address recent basic and clinical studies which suggest that targeting autonomic nerves and ganglia on the large vessels and the h...

journal_title：Current opinion in cardiology

authors： Scherlag BJ,Po S

更新日期：2006-01-01 00:00:00

abstract：PURPOSE OF REVIEW:The appropriate treatment of patients with acute pulmonary embolism who present with right ventricular dysfunction but normal arterial blood pressure, and particularly the potential benefits of thrombolytic treatment in this setting, continue to be highly controversial. In the past year, several well ...

journal_title：Current opinion in cardiology

authors： Konstantinides S

更新日期：2005-11-01 00:00:00

abstract：PURPOSE OF REVIEW:C-reactive protein, a nonspecific marker of inflammation, has recently been proposed both as a marker of low-grade inflammation involved in atherogenesis and as a predictor of disease progression. RECENT FINDINGS:The physiologic functions of C-reactive protein as an anti-inflammatory scavenger molecu...

journal_title：Current opinion in cardiology

authors： Sepulveda JL,Mehta JL

更新日期：2005-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The ability of high-density lipoprotein cholesterol to reverse atherosclerosis and reduce cardiovascular disease has been shown in several randomized controlled trials. One mechanism by which high-density lipoprotein cholesterol protects the vascular system includes hemorheology, the study of blood fl...

journal_title：Current opinion in cardiology

authors： Moriarty PM,Gibson CA

更新日期：2005-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The role of cardiac catheterization in pediatric cardiology has changed significantly in the past 10-15 years. As interventional procedures dominate the field, it is important to examine the recent advances in non-interventional pediatric cardiac catheterization. RECENT FINDINGS:Meaningful and accura...

journal_title：Current opinion in cardiology

authors： Kanter JP,Hellenbrand WE

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Implantation of circulatory assist devices as a permanent alternative to heart transplantation, so-called Destination Therapy, has become a promising new option for treatment of patients with advanced heart failure who are not candidates for heart transplantation. RECENT FINDINGS:The landmark REMATCH...

journal_title：Current opinion in cardiology

authors： Lietz K,Miller LW

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the review is to provide an update on the safety and efficacy of catheter cryoablation. RECENT FINDINGS:Catheter cryoablation is a safe and clinically effective method for ablation of atrioventricular nodal reentrant supraventricular tachycardia. Although the acute procedural success r...

journal_title：Current opinion in cardiology

authors： Friedman PL

更新日期：2005-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Venous thromboembolism, including deep vein thrombosis and pulmonary embolism, represents a significant source of morbidity and mortality in the United States and worldwide. Most acutely ill medical patients are at risk for venous thromboembolism, and prophylaxis is recommended. However, acutely ill m...

journal_title：Current opinion in cardiology

authors： Michota FA

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite similar guidelines, remarkable global differences exist in the management of acute coronary syndromes. This review describes recent insights in global patterns of patient baseline characteristics, treatment strategies, medication use, and outcome in acute coronary syndromes. RECENT FINDINGS:R...

journal_title：Current opinion in cardiology

authors： Sinnaeve PR,Van de Werf FJ

更新日期：2004-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure and diabetes mellitus are frequently associated, and diabetes appears to potentiate the clinical presentation of heart failure related to other causes. The purpose of this review is to examine recent advances in the application of tissue Doppler imaging for the assessment of diabetic hea...

journal_title：Current opinion in cardiology

authors： Marwick TH

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite numerous advances in coronary interventional techniques, the frequent occurrence of restenosis continues to plague interventional cardiology. With the widespread use of drug-eluting stents, there is a need to reexamine critically the roles of the various interventional techniques currently ava...

journal_title：Current opinion in cardiology

authors： Karthikeyan G,Bhargava B

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:High-density lipoprotein cholesterol (HDL-C) has been well established as an inverse predictor of coronary heart disease (CHD), and in recent years, investigations have focused on the genetic regulation of high-density lipoprotein. Although numerous candidate genes contribute to the low HDL-C phenotyp...

journal_title：Current opinion in cardiology

authors： Miller M,Zhan M

更新日期：2004-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This article is an update on DiGeorge syndrome research focusing on the synergy of human and model systems genetics toward the understanding of conotruncal and aortic arch defects. RECENT FINDINGS:The identification of mutations of the human T-Box1 (TBX1) gene and progress on research of Tbx1 functio...

journal_title：Current opinion in cardiology

authors： Baldini A

更新日期：2004-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure prevalence is reaching epidemic proportion in the United States and is associated with significant morbidity and mortality. A large proportion of the mortality is the result of sudden cardiac death (SCD). Clinical trials have demonstrated the superiority of the implantable cardioverter/d...

journal_title：Current opinion in cardiology

authors： Rami T,Shih HT

更新日期：2004-05-01 00:00:00